Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11046)
Related Products (11046)
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Oleic acid-d2
0 ImagesSynonyms: 9-cis-Octadecenoic acid-d2; 9Z-Octadecenoic acid-d2Oleic acid-d2) is the deuterium labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid]. Oleic acid is a Na+/K+ ATPase activator.
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L-Asparagine-15N2 monohydrate
0 ImagesSynonyms: (-)-Asparagine-15N2 monohydrate; Asn-15N2 monohydrate; Asparamide-15N2 monohydrateL-Asparagine-15N2 monohydrate is the 15N-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
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6PPD-quinone-d5
0 Images6PPD-quinone-d5 is the deuterium labeled 6PPD-quinone.
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ATP-13C10 dilithium
0 ImagesCat. No.: HY-B2176S6Purity: 99.94%Synonyms: Adenosine 5'-triphosphate-13C10 dilithiumATP-13C10 (Adenosine 5'-triphosphate-13C10) dilithium is 13C-labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
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L-Methionine-13C,d3
0 ImagesL-Methionine-13C,d3 is the 13C- and deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
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D-Glucose 6-Phosphate-13C6 (disodium xhydrate)
0 ImagesCat. No.: HY-112537S1Purity: 99.6%D-Glucose 6-Phosphate-13C6 disodium xhydrate is a 13C-labeled D-Glucose 6-phosphate disodium xhydrate. D-Glucose 6-phosphate disodium xhydrate is a key central node metabolite in sugar metabolism, serving as the initial metabolite of glycolysis and pentose phosphate pathway, and also a substrate for glycogen synthesis. D-Glucose 6-phosphate disodium xhydrate can act as a metabolic stress signal, especially when phosphoglucomutase (PGI) is inhibited, activating the mTOR pathway, promoting protein synthesis, and thereby participating in the remodeling process of the heart. D-Glucose 6-phosphate disodium xhydrate can be used in research related to non-insulin-dependent diabetes and heart failure.
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Betaine-d9 chloride
0 ImagesBetaine-d9 (chloride) is the deuterium labeled Betaine chloride.
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L-Aspartic acid-13C4
0 ImagesL-Aspartic acid-13C4 is the 13C-labeled L-Aspartic acid (HY-N0666). L-Aspartic acid is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid has no independent analgesic activity. L-Aspartic acid can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid promotes burst firing of central neurons. L-Aspartic acid can be used in studies related to cerebral ischemia and epilepsy.
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Salicylic acid-d6
0 ImagesSynonyms: 2-Hydroxybenzoic acid-d6Salicylic acid-d6 is a deuterium labeled Salicylic acid (HY-B0167). Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation.
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Creatine-d5 monohydrate
0 ImagesCat. No.: HY-W017462SPurity: 99.93%Creatine-d5 (monohydrate) is the deuterium labeled Creatine monohydrate. Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain.
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Calcitriol-d6
0 ImagesCalcitriol-d6 is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 and an agonist of the vitamin D receptor (VDR).
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L-Aspartic acid-d3
0 ImagesL-Aspartic acid-d3 is the d3-labeled L-Aspartic acid (HY-N0666). L-Aspartic acid is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid has no independent analgesic activity. L-Aspartic acid can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid promotes burst firing of central neurons. L-Aspartic acid can be used in studies related to cerebral ischemia and epilepsy.
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L-Cysteine-d3
0 ImagesL-Cysteine-d3 is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans.
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L-Ornithine-1,2,3,4,5-13C5 hydrochloride
0 ImagesL-Ornithine-1,2,3,4,5-13C5 hydrochloride is the 13C-labeled L-Ornithine hydrochloride (HY-W017018). L-Ornithine hydrochloride is an orally active CaSR and p38 activator. L-Ornithine hydrochloride inhibits ROS and supports urea cycle function. L-Ornithine hydrochloride can be used to study kidney diseases involving proximal tubular cell damage caused by oxidative stress or crystallopathy, as well as research related to anxiety disorders.
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L-Arginine-15N4 hydrochloride
0 ImagesSynonyms: (S)-(+)-Arginine-15N4 hydrochlorideL-Arginine-15N4 (hydrochloride) is the 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
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Glycine-13C2
0 ImagesGlycine-13C2 is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
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Glycocholic acid-d4
0 ImagesGlycocholic acid-d4 is the deuterium labeled Glycocholic acid (HY-N1423). Glycocholic acid is a bile acid derivative. Glycocholic acid downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid modulates related bile acid receptor signaling. Glycocholic acid suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA).
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3-Indoleacetic acid-d7
0 ImagesSynonyms: Indole-3-acetic acid-d7; 3-IAA-d73-Indoleacetic acid-d7 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
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Serotonin-d4 hydrochloride
0 ImagesSynonyms: 5-Hydroxytryptamine-d4 hydrochloride; 5-HT-d4 hydrochlorideSerotonin-d4 (5-Hydroxytryptamine-d4) hydrochloride is the deuterium labeled Serotonin (hydrochloride) (HY-B1473). Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
